Men’s Health Blog

Rates of prostate cancer vary widely across the world. It is least common in South and East Asia, more common in Europe, though the rates vary widely between countries, and most common in the United States. According to the American Cancer Society, prostate cancer is least common among Asian men and most common among black men with figures for European men in between. However, these high rates may be affected by increasing rates of detection. Although prostate cancer can sometimes strike younger men, the risk of getting it increases with age and more than seventy percent of men diagnosed with the disease are over the age of sixty five.
Prostate cancer can occur in men only; the prostate is exculsively of the male reproductive tract. Prostate cancer is a disease in which cancer develops in the prostate of the male reproductive system, this happens when cells in the prostate begin to grow out of control and can then invade nearby tissues or spread throughout the body. Large collections of this out of control tissue are called tumors. The tumor usually grows slowly and remains confined to the gland for many years. During this time, the tumor produces little or no symptoms or outward signs (abnormalities on physical examination). As the cancer advances, however, it can spread beyond the prostate into the surrounding tissues (local spread). Moreover, the cancer also can metastasize (spread even farther) throughout other areas of the body, such as the bones, lungs, and liver. Symptoms and signs, therefore, are more often associated with advanced prostate cancer. Prostate cancer may cause pain, difficulty in urinating, erectile dysfunction and other symptoms.
The cause of prostate cancer has not been identified but the cancer is thought to be related to benign prostatic hypertrophy (BHP). The risk factors of prostate cancer include advancing age, heredity, hormonal influences, and such enviromental toxins, chemicals, and industrial products. The best way to try and prevent prostate cancer is to modify the risk factors for the disease that you have control over. You may want to try to eat a low fat diet that is rich in fruits and vegetables. Certain foods, vitamins and minerals have been suggested to decrease your chances of getting prostate cancer, however doctors are still studying more data before any particular food or supplement can be endorsed for preventing the disease. Currently, there are studies looking at selenium, lycopen, vitamin A and other retinoids, vitamin D, vitamin E, and soy for prostate cancer prevention.
Since prostate cancer is a disease of older men, many will die of other causes before the disease can spread or cause symptoms. Deciding on treatment can be daunting not only because there are far better options for treatment today that they were ten years ago but also because not enough relaiable data are available on which to base the decisions. Prostate cancer can be treated with surgery, radiation therapy, hormone therapy, occasionally chemotherapy, or some combination of these.
Most men who have the risk factors do not get the disease, on the other hand men who do get the disease often have no known risk factors, except for growing older. If you think that you may be at risk, you should consult your doctor immediately so that you may be given suggestions on ways of reducing your risk and can plan scheduled check-ups.

Cancer Lett. 2007 Feb 8;246(1-2):201-9. Epub 2006 Mar 24.

Xanthohumol, a prenylflavonoid derived from hops induces apoptosis and inhibits NF-kappaB activation in prostate epithelial cells.

Colgate EC, Miranda CL, Stevens JF, Bray TM, Ho E.

Department of Nutrition and Exercise Sciences, Oregon State University, Corvallis, OR 97331, USA.

There is increasing evidence that certain natural compounds found in plants may be useful as cancer chemopreventive or chemotherapeutic agents. Limited in vitro studies indicate that several prenylated flavonoids present in the hop plant (Humulus lupulus) possess anticarcinogenic properties. The purpose of this study was to investigate the anti-tumorigenic effects of xanthohumol (XN), the major prenylflavonoid in hops, on prostate cancer and benign prostate hyperplasia. BPH-1 and PC3 cell lines were used in our study to represent both non-tumorigenic hyperplasia and malignant prostate cancer. In both BPH-1 and PC3 cells, XN and its oxidation product, XAL, decreased cell viability in a dose dependent manner (2.5-20 microM) as determined by MTT assay and caused an increase in the formation of early and late apoptotic cells as determined by Annexin V staining and multicaspase assays. XN and its oxygenated derivative also induced cell cycle changes in both cells lines, seen in an elevated sub G1 peak at 48h treatment. Western blot analysis was performed to confirm the activation of proapoptotic proteins, Bax and p53. XN and its derivative caused decreased activation of NFkappaB. This work suggests that XN and its oxidation product, XAL, may be potentially useful as a chemopreventive agent during prostate hyperplasia and prostate carcinogenesis, acting via induction of apoptosis and down-regulation of NFkappaB activation in BPH-1 cells.

PMID: 16563612 [PubMed - indexed for MEDLINE]

Phytomedicine. 2006 Nov;13(9-10):732-4. Epub 2006 May 5.

Anti-proliferative properties of prenylated flavonoids from hops (Humulus lupulus L.) in human prostate cancer cell lines.

Delmulle L, Bellahcène A, Dhooge W, Comhaire F, Roelens F, Huvaere K, Heyerick A, Castronovo V, De Keukeleire D.

Ghent University-UGent, Faculty of Pharmaceutical Sciences, Laboratory of Pharmacognosy and Phytochemistry, and Ghent University Hospital, Department of Endocrinology, Belgium.

Chalcones xanthohumol (X) and desmethylxanthohumol (DMX), present in hops (Humulus lupulus L.), and the corresponding flavanones isoxanthohumol (IX, from X), 8-prenylnaringenin (8-PN, from DMX), and 6-prenylnaringenin (6-PN, from DMX), have been examined in vitro for their anti-proliferative activity on human prostate cancer cells PC-3 and DU145. X proved to be the most active compound in inhibiting the growth of the cell lines with IC50 values of 12.3+/-1.1 microM for DU145 and 13.2+/-1.1 microM for PC-3. 6-PN was the second most active growth inhibitor, particularly in PC-3 cells (IC50 of 18.4+/-1.2 microM). 8-PN, a highly potent phytoestrogen, exhibited pronounced anti-proliferative effects on PC-3 and DU145 (IC50 of 33.5+/-1.0 and 43.1+/-1.2 microM, respectively), and IX gave comparable activities (IC50 of 45.2+/-1.1 microM for PC-3 and 47.4+/-1.1 microM for DU145). DMX was the least active compound. It was evidenced for the first time that this family of prenylated flavonoids from hops effectively inhibits proliferation of prostate cancer cells in vitro.

PMID: 16678392 [PubMed - indexed for MEDLINE]

About Virility EX Manufacturing Guidelines

Virility EX prides itself on making quality its firstpriority. All the raw materials used in Virility EX products must passstringent quality control tests before being utilized to produce safe,effective herbal dietary supplements. In addition to selecting the bestpossible suppliers and herbs, all our stock must pass an in-houseinspection before finding its way into a supplement.

The Virility EX enhancement pill is one of many safe, unique, andeffective products Virility EX offers. Our wide range of high-demandsupplements is offered to vendors and retailers at wholesale prices onlyslightly above our manufacturing costs. Weve earned our place at No. 1by offering affordable supplements made from only the finest gradepharmaceutical ingredients.

In addition to high quality, we are also committed to service. Retailerswill be happy to know that we offer private labeling and other servicesthat will help all of our customers, partners, and clients maintain anedge in the competitive herbal supplements marketplaceall the whilebeing certain that theyre offering their customers nothing but the bestherbal supplements available.

For over 15 years Virility EX has been the company that retailers andvendors turn to for high-quality herbal supplements with great pricesand service. For more information on wholesale orderingCLICK HERE

Virility EX Quality Control
All quality control personnel are obliged to adhere to explicit writtenprotocols that are strictly enforced throughout the entire manufacturingprocess. All raw materials used in Virility EX supplements are tested forpurity prior to use. The oversight throughout our quality control process issecond-to-nonewe count on our quality control engineers to reject a batchof product at any stage in the manufacturing process if it doesnt meet ourstrict requirements for quality.

We also keep thorough records throughout the manufacturing process thatundergo analysis by our quality control specialists. The US Department ofAgriculture reviews manufacturing equipment cleaning and maintenanceto makesure that all of our products are completely free of contamination. Ourproduction records for each unit are kept on file for two years past theexpiration date of the unitincluding records related to the units rawmaterials.

Virility EX Quality Control
Product Analysis Every product Virility EX offers is accompanied by aproduct analysis that includes information such as lot numbers foringredients used, as well as a breakdown of herbal supplement components andproduction methods.

Raw Materials Virility EX trusts only the most reputable wholesalesuppliers to provide the ingredients and materials that form oursupplements. Suppliers must furnish a Certificate of Analysis for eachmaterial and all raw materials undergo further analysis by our in-housequality assurance teamwhich means every ingredient used is both authenticand pure.

Packaging Materials Proper packaging is a critical part of ensuringsafety, which means that Virility EX goes the extra mile to make suremislabeling doesnt occur. Designated quality assurance personnel areresponsible for proper labeling, while new labels are crosschecked againstthe master label to detect and correct any errors in the printing process.

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Virility EX Manufacturing Guidelines
General For all forms of supplements the Director of Operations isresponsible for inspecting equipment and overseeing the labeling process.Virility EX is proud to abide by the US Food and Drug Administrations GoodManufacturing Practices. All aspects of the manufacturing process aresubject to both scheduled and surprise inspections by quality control staff.

Blending and Granulation Raw materials undergo an on-site qualityinspection and then processed according to strict, product-specificguidelines. Storage of granulated material is guaranteed to yield fresh,contamination-free product thanks to our specially designed containers.

Encapsulation and Compression After an on-site quality assurance test thegranulated product is encapsulated in a test run. A successful test unitbecomes a sample unit, which is then compared to samples from previousbatches to ensure the maintenance of product quality and integrity.Full-line production does not begin unless the sample unit meets our qualitycontrol standards. Encapsulated products are stored with the same care andattention as our granulated materials.

Liquids Virility EXs commitment to quality means that liquids alsoundergo the same rigorous process of inspection and testing as ourgranulated supplements. Careful production, testing, and storage are themost effective ways to ensure a safe, high-quality product for ourcustomers.

Packaging and Inspection Finished products are subject to inspection byquality control staff that remove defective products such as broken oroverfilled capsules from the lot. Products that meet our high standards arethen packaged for bulk storage or are bottled and labeled for consumer use.Virility EX product packages come with tamper proof seals and FDA-requiredinformation to protect consumers.

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Record Keeping Raw material samples are properly stored for one year pastthe units expiration date, as are samples of finished products.



 

Learn more Everything you need to know about Penis enlargement and penis enlargement pills.

Whenever a discussion about men’s health comes up, diseases that affect the male reproductive organs such as erectile dysfunction are prominent. Many men find it embarrassing to discuss the problem of erectile dysfunction even with doctors. However, after an increase in awareness generated through internet-based pharmacies and medical advancement, men have started opening up. 

With the advent of drugs like Viagra for erectile dysfunction, doctors see more men seeking advice about this condition. Erectile dysfunction or impotence is defined as the persistent inability to attain and maintain an erection, which allows satisfactory sexual intercourse. 

Erection is caused by increasing blood flow to the penis, so anything that stops blood flowing into the penis will result in loss of erection. Viagra pill allows smooth blood regulation resulting in firm erection. However, you should take Viagra only after consulting a registered medical doctor. In addition, Viagra is a prescription drug. You can buy Viagra only after obtaining a valid prescription from a doctor. You can also buy Viagra online, as many internet-based pharmacies are licensed by the government to sell Viagra on providing a valid prescription online. 

Common fear in men 

Many men think that erectile dysfunction is a sign of their weak masculine power. These fears often result in developing serious psychological problems with men. However, it is important to be aware of the fact that erectile dysfunction is common. In majority of men, it is not caused by a deficiency of male hormones or even lack of masculinity. 

Viagra – Erectile dysfunction drug

Drugs like Viagra have dramatic effects on men with erectile dysfunction. Viagra has helped men to get rid of their imaginary fears by treating erection problems. Men who use Viagra frequently have reported huge success in countering their erection problems. 

Viagra is not a miracle drug but works on a simple pattern of enabling blood circulation in the penis. You might have observed why erectile dysfunction is more common in patients with conditions like heart disease, high blood pressure, high cholesterol level and diabetes. This is due to inadequate flow of blood in the body and erectile dysfunction occurs when arteries of the penis narrow and result in less blood circulation. 

Erectile dysfunction treatment has been revolutionised by the introduction of medications like Viagra, which is an orally taken tablet. Viagra tablets have produced effective results in about 70 percent of men with erectile dysfunction.

A major drug maker, Pfizer is the manufacturer of Viagra and introduced this anti-impotence drug in the world markets in 1998. A year later after its launch, in 1999, Pfizer generated $1,033 millions due to sales of Viagra. This drug has broken all records of popularity among men with erectile dysfunction.

The popularity of Viagra can also be gauged from a survey that was conducted to measure the most popular keyword among the internet users. The word ‘Viagra’ stood apart as the most frequently searched keyword in one of the major search engines. This also signifies the importance of Viagra in the life of men with erectile dysfunction.

Viagra helps men with erectile dysfunction or impotence to treat their problem. After taking Viagra, men get firm erections that are necessary for satisfactory sexual intercourse. Viagra helps in regulation of the flow of blood, which often circulates in less quantity into some internal parts of the penis. Viagra works only under sexual stimulation and is not an aphrodisiac, as many men think about it. It cannot increase your sex drive.

Who can take Viagra?

Men with erectile dysfunction problems can take Viagra after consulting a registered medical doctor. Viagra is a prescription pill and to buy it without obtaining a valid prescription from a doctor invites complications. It can result in side effects or cause allergic reactions due ingredients of Viagra.

You can take Viagra orally approximately one hour before sexual activity and the dosage of Viagra should not exceed more than one tablet in a day. Otherwise, it can result in side effects.

Side effects of Viagra

The most common side effects visible among men after taking Viagra may include headache, facial flushing, and stomach troubles. These effects are generally mild and go away after some time. However, if the side effects persist for a long time, then you should consult a doctor. Apart from these side effects, Viagra is a safe and effective medication that treats erection troubles.

Availability of Viagra

Viagra is available in many countries of the world including the UK and European nations, as the European Union has approved the use of Viagra long back. Viagra is also available in the US after FDA approved it.

Viagra is also available online, as many reputed and trustworthy online pharmacies sell it by providing professional service. Prescriptions are provided to patients by registered doctors online. This saves their lot of time. You can also buy Viagra online, as it is quite a simple process.

Earlier I blogged about Australian Skeptic of the Year, Loretta Marron, and her lecture at the Hobart Skeptics conference about the continuing battle against 'weight loss drug' claims. Now the USA has discovered a little something about a popular company - Berkeley Premium Nutraceuticals:

A federal court jury on Friday found the owner of a company that sells "male enhancement" tablets and other herbal supplements guilty of conspiracy to commit mail fraud, bank fraud and money laundering.

Geeze, you'd think that just the pills being bad was bad enough...

Steve Warshak is founder and president of Berkeley Premium Nutraceuticals, which distributes Enzyte and a number of products alleged to boost energy, manage weight, reduce memory loss and aid restful sleep.

Television ads for Enzyte feature "Smiling Bob," a goofy, grinning man whose life gets much better after he uses the product.

Warshak, 40, could face more than 20 years in prison and his company could have to forfeit tens of millions of dollars.

Ah dear. Never mind, maybe he can work on the memory loss in regards to where the money went...

Some former employees, including relatives of Warshak, pleaded guilty to other charges and cooperated with prosecutors. They testified that the company created fictitious doctors to endorse the pills, fabricated a customer-satisfaction survey and made up numbers to back claims about Enzyte's effectiveness.

News flash - wearing a white coat? Don't make you a real medical expert. Good riddance to bad pill claims and here's to many more court-cases that show them for what they are!

Impotence or Erectile Dysfunction refers to the inability to obtain an adequate erection for satisfactory sexual activity. It affects the lives of many middle-aged men and their partners to one degree or another. Although, it’s more common in males older than 65, one can experience impotence at any age. Failure to achieve an erection less than 20% of the time is not unusual but failure to achieve an erection more than 50% of the time indicates a problem that should be looked into.

The easiest, safest way to a longer, thicker penis is to exercise. It’s a really simple technique that has been around for thousands of years. Men have always obsessed about the length and girth of their penises, so penis enlargement techniques were developed early and have been used throughout human history. There are two large groups of penis exercises: penis stretching exercises and exercises aimed to increase the girth of the penis.

The body's ability to adapt and change when subjected to tensile force is well documented. Cells within an area exposed to such force divide and multiply, resulting in an increase in tissue mass. Penis stretching techniques rely on this principle as do the use of penis weights and stretching devices. Manual stretching is considered to be the safest for beginners, as it does not result in long-term reduction of blood circulation to the glans of the penis, which is a frequent result of a lack of proper technique in the use of weights or stretching devices.

Penis stretching techniques are simple to learn and perform. They involve gripping the head of the flaccid penis and gently pulling forward. The stretch should not be so intense as to cause pain or discomfort, but should merely stretch the penis to its maximum comfortable capacity. A basic exercise would be to hold the stretch for 15-30 seconds before relaxing. The process would then be repeated 10-15 times to complete the session.

These techniques slightly break down the penile chambers known as the Corpora Cavernosa and Corpus Spongiosum by expanding them more than usual. During the course of the day and the night, your body heals and repairs these tiny penile tissue fibers, helping you achieve a bigger penis.

It's the same thing that orthopedic doctors will do to your bones when they need to speed up the healing process that naturally occurs in broken bones: they will add weights or they will progressively stretch your bones to encourage the formation of new healthy tissue.

Penis stretching exercises have been around for hundreds, if not thousands, of years. And yet very few independent medical studies have analyzed their effects on the human body.

There is money to be made in plastic surgery, because who would pay $5,000 to $10,000 or more to lengthen their penises when they can achieve the same results naturally, without any risks of permanent injury and under $100? The lack of peer-reviewed studies can make your average urologists advise you against trying anything potentially dangerous.

You might want to consider joining an exercise program. Natural penis enlargement exercise program will include all the relevant sessions to aids in penis gains. Examples include a warm up, jelq session followed by other exercises and, at the end, the cool down routine.

Penile exercises represent an effective method to add permanent growth over months of regular practice. There are no overnight miraculous gains, but in the end you will be happy with the result of your personal effort.